While trying to copy a Virtual Machine onto one of my back-up drives I ran into the "Not enough space on drive" error. Of course the drive I was copying to was 500GB so I knew that I had space.

After a little bit of checking I realized that the drive was still FAT32. I had never converted it to NTFS. FAT32 wont let you copy anything over 4GB.

Anyway, to fix this is pretty easy, you can use the command line tool convert.exe to change the file system from FAT32 to NTFS. 

the following command will do the trick --   convert D: /fs:ntfs (where D is the drive you want to convert)

Now I am able to copy over those 10GB files. :)

I know this is old news to some but..... It is easy to forget what you dont use ;)

Doc